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The lncRNAs MIR100HG and MIR22HG are the host genes of miR-100/125b and miR-22-3p/5p, respectively, activating the Wnt pathway by upregulating the expression of these miRNAs

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MC4R integrates anorectic signals derived from alpha-melanocyte-stimulating hormone (MSH) and orexigenic signals generated by agouti-related peptide (AGRP) [3, 4]

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