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It must be the same drug chemically and have the same medical effect

Factors Requiring Dosage Modifications Several factors might need a change in B12 injection dosage

32 Vegans and even lacto-ovo-vegetarians with only a small intake of eggs and dairy foods may require supplemental vitamin B 12 from fortified foods or supplements

In patients with chronic disease or infection, ferritin may appear normal even when iron stores are low

In contrast, it has been demonstrated that overexpression of NNMT in mouse liver leads to a decrease in NAD + levels ( in vitro experiments that NNMT promotes the migration and invasive ability of esophageal squamous cell carcinoma (ESCC), and NNMT also promotes the process of epithelial mesenchymal transition (EMT) by affecting the post-transcriptional modification of E-calmodulin

5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia