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Description
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As the metastatic tumors develop, TGF- in the TME may resume its pro-tumorigenic roles as a mediator of immune suppression, EMT, invasion, and further dissemination
demonstrated that senescent pancreatic ductal adenocarcinoma (PDAC) cells in mice activated endothelial cells through the release of SASP factors into the tumor microenvironment [39]
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Epub 2020 Dec 30
