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This is a stressor for the body, causing hypoxia of intestinal cells due to redistribution of blood in the body, hyperthermia and dehydration [158, 159]

Research literature suggests it may influence hormone-related signalling pathways and stress-response modulation in controlled experimental models

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Disparate results are likely due to study design issues, often linked to a lack of understanding of vitamin C pharmacokinetics and requirements (19, 20)

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