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Ethics statement The animal investigations were conducted strictly with the Principles of Laboratory Animal Care of the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) of the Jeonbuk National University Hospital

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However, there is limited evidence of its use due to the low number of published trials, and it should not be yet disregarded until future studies further assess potential benefits

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Distinct from other cell death modalities, ferroptosis involves glutathione (GSH) depletion, inactivation of glutathione peroxidase 4 (GPX4), and the lethal accumulation of lipid peroxide

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