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This sex bias highlights the need for female-focused experimental models to better understand the biological context in which cannabinoid-based strategies may exert their effects ( We have recently demonstrated that non-invasive oral administration of cannabis oil improved arterial hypertension, dyslipidemia, and hepatic steatosis in both male and female Wistar rats fed a sucrose-rich diet (SRD) during 3 weeks ( de novo lipogenesis and -oxidation of fatty acids), fibrosis, and oxidative stress related to MASLD, as well as changes in the endocannabinoid system (ECS), aiming to identify new molecular mechanisms involved

The results showed that rivastigmine had significant efficacy in the treatment group compared with the placebo group and that the efficacy of the 10 cm 2 patch was similar to that of the capsules

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Feno significantly reduced the plasma ACs levels, especially LCACs, in VPA-induced hepatotoxic mice and restored the ACs levels to normal, demonstrating that it could facilitate the hepatotoxic effects of VPA by activating the fatty acid -oxidation function