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Most published research comes from rodent and cell culture studies conducted primarily by one research group

Cell 2017;168:657-69

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In the prospective Framingham Offspring Study, moderately elevated bilirubin concentrations were found to be associated with a lower risk of cardiovascular disease, coronary heart disease and myocardial infarction ( 90 )

It is very important to note that the noxious effects of ROS and pro-inflammatory factors presents in the follicular fluid of ENDO patients (such as IL-6, TNF-) would be even more accentuated in human ovary where oocytes are exposed to follicular fluid at higher concentrations and for longer periods of time than in the current study

From these results and considering the limitations discussed, we conclude that the assessment of functional MEG connectivity and the subsequent characterization of the brain network structure may be a useful approach to understand AD and provide new strong evidences of the usefulness of combining both methodologies to study brain function from multivariate neuroimaging data in health and disease