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Statements Author contributions J-YZ: Writing original draft, Writing review & editing

It has been documented that an electrophilic metabolite of acetaminophen N-acetyl-p-benzoquinone imine (NAPQI) reacts with CysSSH or GSSH forming mixed disulfides NAPQIH 2 -SSCys or NAPQIH 2 -SSG, respectively [73]

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For instance, oral dosing of Vitamin C functions principally to enhance anti-oxidant and immune related functions of Vitamin C

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