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Endocrinology 1996, 137:2968-2978

There have been reports of pulmonary aspiration (when food or liquid from the stomach enters the lungs) in people taking GLP-1 medications, including Zepbound while undergoing surgery requiring sedation, even when instructed to fast before the surgery

These fluctuations are meaningless noise that can trigger anxiety, frustration, and counterproductive behavioral responses

8.2 Cost-effectiveness and health economic implications The elevated cost of acquisition of GLP-1 receptor agonists convey major challenges for healthcare systems, with yearly treatment expenses between $10,000 and $15,000 USD, markedly surpassing those of conventional diabetic drugs (Kong et al

However, it is crucial to recognise that medication is not a substitute for lifestyle interventions but rather an adjunct to support metabolic health

Recent advances in PET imaging and fluid biomarkers are improving monitoring of GLP-1RA treatment response [65]