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This review examines studies on iron metabolism, regulation via the hepcidin-ferroportin pathway, myocardial energy, oxidative stress, and clinical trials of iron supplementation or reduction in heart failure, chronic kidney disease, the elderly, women, and athletes
Some common approaches include alternate-day fasting, 5:2 fasting (eating a normal diet five days per week and fasting two days a week), and daily time-restricted fasting (eating normally but only within an eig
review evidence linking components of this pathway to human disease and discuss potential strategies for therapeutic intervention.
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