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In humans, P-gp is the product of the MDR1 gene (7) and was among the first identified members of the enormous family of ATP-dependent transporters known as the ABC transporter family (72)
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The key distinction: MOTS-c acts as a signaling molecule that tells cells what to do with energy substrates
Whether the depletion of microglia has an impact on the myelination of the tNs has not been assessed but the effect is likely to be time and model-dependent
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The physicochemical parameters of BET and BJH methods were listed in Table 1
