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Comparison of RNA-seq and proteomics data revealed nine shared transcripts upregulated by PQS treatmentTFR1, high mobility group protein HMGI-C2 (Hmga2), U6 snRNA-associated Sm-like protein3 (Lsm3), U6 snRNA-associated Sm-like protein5 (Lsm5), non-histone chromosomal protein HMG-17 (Hmgn2), prefoldin subunit 1 (Pfdn1), high mobility group protein HMG-I/HMG-Y (Hmga1), SAFB-like transcription modulator (Sltm), and mesencephalic astrocyte-derived neurotrophic factor (Manf) (Supplementary Fig
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Thrombin may also exert its function through other receptors and proteolysis of specific components in the extracellular matrix (e.g., fibrinogen) under physiological and pathological conditions (e.g., epileptogenesis, see Dityatev, 2012)
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Furthermore, FOXM1 and FOXO3a together compete for the same DNA sequences for binding
