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Mechanistically, V-9302 sustained glutamine uptake by CD8 + T cells, by promoting the compensatory upregulation of the glutamine transporter ATB 0,+ / Slc6a14 , in CD8 + T cells, to support de novo glutathione synthesis and improve redox balance in T cells

The mean weight loss of 12.07 kg in the survey represents a meaningful reduction in estrogen-producing tissue

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Muscle Imbalance: Weakness or imbalance in the muscles around the knee, particularly the quadriceps, can alter patellas tracking and increase stress on specific areas of cartilage

Other Dietary Sources Worth Noting While concentrations are considerably lower than in mushrooms, ergothioneine can also be found in: Animal products: Liver (especially kidney and red blood cells contain moderate amounts) These levels reflect the ergothioneine animals consumed from their own diets Legumes: Black beans, kidney beans, and red beans (especially when grown with mycorrhizal fungi) A 2023 study found black beans showed up to 72 times more ergothioneine when grown with beneficial soil fungi [2] Grains and fermented foods: Oat bran and wheat (particularly when cultivated with specific soil fungi) Tempeh, natto, miso, kimchi, and sauerkraut contain small amounts Spirulina contains relatively high amounts compared to other non-fungal sources Typical dietary intake ranges from 5-20 mg per day depending on mushroom consumption patterns

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