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Aboalam HS, Hassan MK, El-Domiaty N, et al

The current concern is that excessive or inappropriate antioxidant interventions in aging CAP instead disrupt normal cell signaling pathways and inhibit the beneficial effects of ROS and lipid peroxidation products on disease, such as by mediating the physiological apoptosis of immune cells (213)

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This phase involves various enzymatic reactions that introduce or expose functional groups on the molecule, making it more amenable to subsequent modifications in Phase II metabolism or easier for elimination from the body
