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doi: 10.1016/j.biortech.2021.126408 47 NeoriA.GuttmanL

Activation of the UPR generally serves as a readout for ER stress, but it is not clear what diminished ER stress implies in terms of an actual accumulation of unfolded proteins, particularly because some stressors, such as palmitate loading, activate the UPR apparently independent of the protein folding process (Volmer et al., 2013)

Any temperature excursion above 8C for more than 24 hours risks peptide degradation that home testing cannot detect

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