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To address these challenges, various delivery methods have been investigated, including viral vectors, non-viral vectors, and rational design strategies such as chemical modifications, cationic liposomes, polymers, nanocarriers, and biocoupled siRNAs, aimed at enhancing stability and intracellular delivery (Liu F

doi: 10.1016/j.brainres.2010.03.091, 46 KeeserD.MeindlT.BorJ.PalmU.PogarellO.MulertC.et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 248.Gao X., Kim H.K., Mo Chung J., Chung K

Administration of interleukin-1 at birth affects dopaminergic neurons in adult mice

In recent years, much effort has been made to adapt reaction conditions to allow for the use of more environmentally friendly solvents such as water or ethanol, which are polar and capable of hydrogen bonding

Similar to the glutamate transporters above, glutamate receptors are primarily located on the cell membrane of the neuron and bind to glutamate from the synapse