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The induced reduction in the lactate/pyruvate ratio in healthy human volunteers during exercise suggests that naftidrofuryl increases the efficiency of aerobic metabolism in oxygen-deprived tissues [133]

In this review we will address how (i) cellular H 2 O 2 is produced and how it regulates certain signaling pathways, (ii) tumor cells cope with enhanced H 2 O 2 levels to escape from oxidative stress, (iii) potential redox-sensors might be correlated with tumorigenesis, and how (iv) H 2 O 2 -modulated processes/pathways might be used as therapeutic targets

doi: 10.3389/fimmu.2023.1148595 80 VairaLAGessaCDeianaGSalzanoGMaglittoFLechienJRvet al

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A comprehensive understanding of each enzyme's contribution to ferroptosis could pave the way for developing targeted therapeutic agents for related diseases

Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide
