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Latest metabolic screening has shown a preferred accumulation of many metabolites and overexpression of genes of glutamine synthesis (glutaminolysis) pathways (e.g., glutamate, alpha-ketoglutarate (AKG), Glutamic pyruvate transaminase (GPT2), and Glycine amidinotransferase (GATM)) in IL-4-induced M2 macrophages (Biswas 2015)

Clin Chem Lab Med 42(2):228234 Donnelly JG, Pronovost C (2000) Evaluation of the Abbott IMx fluorescence polarization immunoassay and the bio-rad enzyme immunoassay for homocysteine: comparison with high-performance liquid chromatography

These findings could mark a major advancement in the treatment of CHB, offering patients a more effective strategy to manage the disease

Hence, an understanding of the biological mechanisms and molecular mechanisms is urgently needed to develop new therapeutic strategies for the comprehensive treatment of pancreatic cancer

2012 doi: 10.1089/ars.2012.4553

Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S et al (2012) Accumulation of p62/ SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma