autism+glutathione Tylenol can lower the body's key antioxidant, glutathione, though this isn't seen on routine labs. But mechanistic data ≠ clinical proof, so we still need good trials. The Tylenol–autism link isn't clear Frontiers | Improving Antioxidant Capacity

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The best practice is to always let the water run down the side of the vial to ensure the gentlest possible reconstitution