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Retinas were blocked in retina staining solution (5% goat serum, 1% BSA, 1% Triton X-100) for 3 h at RT, followed by overnight incubation with primary antibody at 4 C

Dysesthesia, an abnormal sensation often described as tingling, burning, or numbness in the skin, appeared in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo

Over time, the hyaluronic acid in synovial fluid breaks down, contributing to joint pain and stiffness in people with osteoarthritis

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