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Side Effects: Gastrointestinal discomfort, fatigue

No tolerance development to the lipolytic effects was noted in these studies, suggesting that unlike beta-2 agonists (which rapidly desensitize their receptors), beta-3 receptor activation may not produce the same downregulation pattern

HAM-D and MADRS are the most commonly used tool to assess depressive symptoms, and as a primary outcome of different clinical trials for depression (Rush et al., 2004

Vitamin D Vitamin D plays an important role in bone health and muscle function
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