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Also, in an animal model of AD, intracellular accumulation of the tau protein was shown to produce a decrease in mitophagy and subsequent mitochondria dysfunction that affected synaptic communication (Hu et al., 2016

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Viability was assessed 72 h after addition of 4-OH-TAM

Some patients report noticing improvements in energy and mood within one to two weeks of beginning treatment, while others may require a series of sessions before noticing meaningful changes
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