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For instance, in Caenorhabditis elegans , daf-7 was shown to encode a homolog of GDF11 and MSTN , while in fruit flies ( Drosophila melanogaster ), myoglianin (Myo) was found to exhibit the highest sequence homology to GDF11 and MSTN 10,11,12,13

Traditional swallowed forms have limited effectiveness due to digestive breakdown, but sublingual troches and liposomal formulations improve absorption significantly