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HCV replication intermediates, in particular dsRNA, are generally sensed by RLRs 40,41,42,43 , despite the recently discovered FAD-capping of the viral genomes 44
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J Neurochem 79 : 11131121
Moreover, a phenotypic study on human primary macrophages and stellate cells suggested that AXA1125 can inhibit lipopolysaccharide (LPS)-induced TNF- expression in M1 macrophages and increase the secretion of anti-inflammatory chemokine C-C motif ligands by M2 macrophages, as well as reduced Pro-C3 and HSP47 expression in HSC
WO, 130395, 2010
