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The tissue becomes sensitized, developing localized immune memory that triggers faster and stronger responses with each subsequent injection

Faraone SV, Asherson P, Banaschewski T, et al

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Given that excessive build-up of collagen is considered a hallmark of fibrosis, we wanted to see whether this molecule has a role in tissue stiffness. They started by looking at the biological and mechanical features of lung tissue from people with lung fibrosis and compared this to healthy lung tissue

These preparations, while still neonatal in origin, represent a more intact and three dimensional environment than dissociated neurons