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Pothula SP, Xu Z, Goldstein D, Merrett N, Pirola RC, Wilson JS, et al
In the selenite-induced cataract model, subcutaneous injection of RGNPs improved lens opacity and decreased the mRNA and protein levels of proteins associated with the lens (A-crystallin and A1-crystallin) senescence markers (p16 and p21) and the activated Sirtuin (Sirt) 1/Nrf2 pathway
Overall, 5-Amino-1MQ represents a novel class of NNMT inhibitors with the potential to impact multiple physiological pathways
Psychopharmacology (Berl) 130, 343351
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Govind, A
