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Glutathione S -transferase P11 (GSTP11) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaaction with the C terminus

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doi: 10.4049/jimmunol.1002315

A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy