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Weiss R

Preclinical studies in animals have shown that opioid peptides do not induce central side effects [255,256,257], positioning them as a potentially effective and safe alternative to conventional analgesicsmany of which (e.g., diclofenac) impair wound healing or have a limited systemic penetration but still carry a risk of central nervous system (CNS) side effects (as is the case with regular opioids)

[DOI] [Google Scholar] 155.Sever M., Klicek R., Radic B., Brcic L., Zoricic I., Drmic D., Ivica M., Barisic I., Ilic S., Berkopic L., et al

Reker, D

43, 44 Urotensin-II has also been shown to function as a potent vasodilator in some isolated vessels

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