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Targeting the DNA repair endonuclease ERCC1-XPF with green tea polyphenol epigallocatechin-3-gallate (EGCG) and its prodrug to enhance cisplatin efficacy in human cancer cells

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730 FtMt protein expression is significantly upregulated in MCAO/R mice, and the absence of FtMt promotes free iron deposition and lipid peroxidation, which aggravates ferroptosis and brain injury caused by MCAO/R

E.Hernndez-MendozaA.Gonzlez-CrdovaA

The reaction mechanism of Casiopeinas is not well known, but from these results we suggest two probable mechanisms derived from these copper compounds, for the treatment of cancer