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The dynamic redox interplay between NAD + and its reduced counterpart NADH is fundamental to metabolic processes, particularly in maintaining cellular energy balance and redox homeostasis [4, 5], affecting cellular energy balance and stress response mechanisms [6]

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Inflammation requires the induction of pro-inflammatory pathways, which govern tissue activation in response to insults, and the subsequent functional and metabolic licensing of immune cells (leukocytes) residing in tissues or recruited from blood

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Li N, et al

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