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It is conceivable that there is a high possibility of acquired resistance after treatment with KRAS (G12C) inhibitors 228

[DOI] [PubMed] [Google Scholar] Williams DE, Wareham NJ, Cox BD, Byrne CD, Hales CN, Day NE

& Weisskoff, R

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J Exp Bot 66:29012911 Hicks LM, Cahoon RE, Bonner ER, Rivard RS, Sheffield J, Jez JM (2007) Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana