glutathione transferase mechanism The Multifaceted Role of S-Transferases in Health and Disease Schematic representation of the structure

Moonlighting functions Many of the proteins involved in the ascorbateglutathione cycle reside in different intracellular compartments where they can have moonlighting as well as enzymatic functions

Several of these bioregulators are relevant to autoimmune disease through organ-specific mechanisms: Thymalin is a thymus-derived peptide that supports thymic function and T cell maturation

In a chinchilla model of acute acoustic trauma, HPN-07 itself enhanced auditory/cochlear functional recovery, and reduced loss of cochlear HCs, afferent nerve fibers in the spiral lamina and fibrocytes within the spiral ligament 33

S.PfeifferS

doi:10.3390/jcm13082176

M.de la ChapelleA.et al (2004)