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NAD+ Optimization: TBI depletes NAD+, a critical coenzyme for ATP production

Key points In vertebrates, the enteric nervous system (ENS) is critical for gastrointestinal function

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After brain injury, the Shh signaling pathway induces SVZ progenitor cells to produce large amounts of transcription factors, which determine cell differentiation types through time-dependent mechanisms and concentration gradients, compensating for brain cell losses (43)

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