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In contrast, we occasionally hear from others who experience pain with B12 shots

Feb 2010;16(1):1-5

The British Dietetic Association recommends that vegans take a daily supplement of at least 10 g or a weekly supplement of 2,000 g to ensure adequate intake

Suppliers sell the reference standard as an iodide salt, and the literature describes it as a selective NNMT inhibitor with an IC50 near 1.2 micromolar, meaning it shuts the enzyme down at low concentrations without hitting related enzymes

Single missed doses have minimal impact on cumulative results
