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Chemical constituents from hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells

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doi: 10.1016/S0002-9440(10)64354-4

Crystallographic coordinates of the ternary complex of Pt GSTF8 have been deposited in the PDB as 8AGQ

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In a single-center, randomized, double-blind, placebo-controlled trial conducted at the Emergency Department of a hospital in Brazil, 140 patients with severe COVID-19 infection and oxyhemoglobin saturation of less than 94% or respiratory rate higher than 24 breaths/minute were randomized to receive N-acetylcysteine 21,000 mg (approximately 300 mg/kg) for 20 hours or dextrose 5% (placebo)