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It is thus of relevance to understand whether the metal core of metallothioneins can originate metal sulphide nano-crystals from the -elimination mechanism and whether these nano-crystals can play a role in the organ toxicity of accumulated metals, especially in the kidney

In addition, the PI3K/Akt/mTOR axis overactivation not only prioritizes glycolytic flux, but also governs the intracellular availability of essential amino acids such as glutamine (Gln) and arginine, effectively linking glucose consumption to the protein synthesis machinery required for cytokine production

doi: 10.1016/S0960-8966(97)00046-1 84

Vitamin B6 is required for the production of Serotonin, a brain neurotransmitter that controls mood, appetite, sleep patterns and sensitivity to pain

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[DOI] [PMC free article] [PubMed] [Google Scholar] 351
