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Glucose-mediated Induction of TGF-1 and MCP-1 in Mesothelial Cells In Vitro Is Osmolality and Polyol Pathway Dependent

For pathway reconstitution experiments, the codon-optimized BCCT gene (Aci1347) was cloned into plasmid pGEX-6P-1- cntAB using the In-Fusion cloning system (Takara) yielding construct pGEX-6P-1- cntAB-bcct
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Tirzepatide is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity

BunielloAMacArthurJALCerezoMHarrisLWHayhurstJMalangoneCet al

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