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Researchers observed that enhanced dopaminergic signaling in the mesolimbic reward system modulates food reward and motivation to eat, while increased noradrenergic signaling in the hypothalamus promotes sympathetic tone and energy expenditure, and serotonergic enhancement in the hypothalamic satiety circuits reduces food intake
Cell Transpl
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Do not scratch the affected area
A phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCGrefractory and BCG-intolerant patients
These bidirectional modulatory effects suggest interaction with aminergic tone regulation rather than direct receptor agonism
