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In vivo experiments Male Nox2 wt (n = 45) and Nox2 / (n = 45) mice, ages 79 weeks were used for intratibial injections of luciferase-expressing RM1 cells, and performed twice

Using a human-relevant mouse model of metastasising breast cancer, in which experimental study, breast carcinoma cells are injected into pre-cleared mammary fat pads (orthotropic transplantation), activation of GRs at distant metastatic sites was found to be required for colonization and heterogeneity of metastases, as well for reduced survival of transplanted mice [22]

doi: 10.1002/pro.3321 224 SandeepVGAEChanLS

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Sire breed and non-genetic effects on calving survey traits

Hepatokines Hepatokines are a diverse family of cytokines secreted by the liver, and have been shown to exert autocrine, paracrine, and endocrine functions in metabolic disorders