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10.1016/j.chembiol.2015.11.016 194 ShimizuK.OhtakiK.MatsubaraK.AoyamaK.UezonoT.SaitoO.et al

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The results from in vivo experiments on rats in a maze, monitoring social interactions, locomotor activity, and cage tests, showed that pure asiaticoside, and methanol or ethyl acetate extracts of Centella asiatica had anxiolytic activity
