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[69] [70] Compliance with the updated labeling regulations was required by 1 January 2020 for manufacturers with US$10 million or more in annual food sales, and by 1 January 2021 for manufacturers with lower volume food sales

But more physiologic does not mean no oversight needed. It still warrants a clear rationale, appropriate bloodwork, and monitoring over time

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102 Based on this insight, we tested and confirmed the hypothesis that iron chelation prevents protein nitration in mitochondria and protects against APAP hepatotoxicity

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