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Description
Adolescent female rats treated with (THC) for 11 days and left until adulthood presented significant "behavioral despair' (forced swim test) paralleled by anhedonia (sucrose preference)

Chen H, Tan H, Wan J, Zeng Y, Wang J, Wang H, Lu X

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However, cultured rat astrocytes can also synthesize the glutamate needed for GSH synthesis from ketoglutarate, glutamine, or proline and can generate glycine from serine (Dringen and Hamprecht 1996, 1998)

Concerning the systems studied, the GSSG/GSH redox potential shows modest variability, owing to the relative remoteness between the sulfur and the other acid-base functions in the molecule
