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This study illustrates the importance of inhibiting the glutathione metabolic pathway regulated by Nrf2 for tumor therapy, and at the same time provides a new idea for the treatment of malignant tumors with IDH1 mutations

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Recent findings indicate that G6PD is dynamically O-GlcNAcylated at serine 84, which dramatically increases the enzymatic activity of G6PD

257 In addition, the chance of pregnancy is lower if damage to motility or morphology affects a large percentage of sperm, abnormalities in sperm function are identified, or the female partner is over 40 years old