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This raises the possibility that other infections that primarily affect the periphery may not have been thoroughly examined for their neurological impact in human disease

Some of these studies have combined functional analyses of mitochondrial bioenergetics in PBMCs with either metabolomic studies to identify differentially-expressed mitochondrial-based molecular profiles [62] or genetic signatures [63] as markers for predicting disease progression in MASLD

Accessed 10 Nov 2023 Green RM, Travers AM, Howe Y, McDougle CJ

Trichloroethylene: mechanisms of renal toxicity and renal cancer and relevance to risk assessment

It must be noted, however, that although our findings shed light on the interactions between HSF1 and the UPR ER , the exact mechanisms operating in different animal models await further clarification