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doi: 10.3390/molecules26123486, 32

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While both vaccines have demonstrated promising immunogenicity and safety profiles in early and ongoing clinical trials, these parameters are yet to be finalized pending the completion of Phase III trials

At a pH above the pKa for the functional group it is deprotonated

Its ability to cross the bloodbrain barrier in laboratory models, combined with a relatively long plasma half-life compared to other small neuropeptides, has contributed to its enduring relevance in neurochemistry research