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Frontiers in Nutrition, 8, 782912

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Gefitinib (a selective EGFR TKI) (10 M) could enhance arsenic trioxide (0.6 M) induced differentiation of NB4 APL cells through promoting ROS production and activation of ERK pathway [34]
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In contrast, lower than normal [ 14 C]-propionate or [ 14 C]- N 5 -methyl-tetrahydrofolate incorporation after fusion of cell lines with polyethylenglycol confirms that the two patients possess the same genetic defect (Watkins and Rosenblatt, 2013)

While promising, these innovations are still being researched and require further clinical validation [25]
