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Skeletal muscle consumes large amounts of molecular oxygen and can produce large amounts of ROS [77]
Conditions like pernicious anemia or Crohns disease can also block absorption and cause deficiency
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Presenting signs include: Severe, persistent upper abdominal pain radiating to the back Persistent vomiting Fever Jaundice Stop the drug and seek emergency care if these symptoms appear because pancreatitis can progress quickly and require hospitalization

Terrill J, et al