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26 B12 present in food products requires gastric enzymes such as pepsin and stomach acid to detach it from protein, while supplemental forms of B12 are typically in an unbound state and do not require this process for absorption

10.1016/j.ijbiomac.2017.10.094
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10.1016/j.intimp.2016.10.018 29 FuY.CaiJ.XiM.HeY.ZhaoY.ZhengY.et al (2020)

Many cases of sub-clinical hypothyroidism are transient
