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Rare serious risks include allergic reactions to B12 or, in predisposed individuals, thrombotic events

doi: 10.1371/journal.pone.0250165

Researchers intending to work with the lyophilised version should ensure access to DMSO or a similar solvent for proper handling

To test the possible increase in potency of the two drugs when given simultaneously, we injected a total volume of 4 ml of combined doses of L838,417 and CLP257 in a fixed dose ratio of \([{\mathrm{L 838,417]/[{\mathrm{CLP 257]\) = 1:55, given the relative EC50s of the two drugs calculated from the respective dose response curves with a priori assumption on the collapse at high doses of L838,417 (Fig

A full-thickness skin wound with a diameter of 6 mm was created on the dorsal region of each mouse

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