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doi: 10.21037/jtd-cus-2020-012 35

7 Moreover, in acute myeloid leukemia (AML), high levels of signal transducer and activator of transcription 5 (STAT5) activate glycolytic genes and histone Kla, notably H4K5la, promoting PD-L1 transcription accompanied by the interaction of PD-1/PD-L1 and CD8 + T-cell activation, eventually leading to immunosuppression
A-Type K + Channels Voltage-dependent potassium (Kv) channels composed of Kv1 and Kv4 subunits underlie the transient A-type K + current ( I A ) in hippocampal, cortical, and NAc medium spiny neurons, where they influence a wide range of functions, including the shaping and propagation characteristics of action potentials, and complex cognitive processes (Hoffman et al., 1997

Gilloteaux J, Eze N, Jamison JM, McGuire K, Summers JL
